49 articles - From Friday May 30 2025 to Friday Jun 06 2025
Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…
| Endoscopy |
|---|
Curriculum for training in peroral endoscopic myotomy (POEM) in Europe (Part II) - Best Practice Techniques: European Society of Gastrointestinal Endoscopy (ESGE) Position Statement. 14: In the absence of adverse events, resume fluids on day 1, soft diet on day 3, and normal diet on day 7 post-POEM. 15: ESGE recommends against the routine use of standard or computed tomography fluoroscopic esophagrams after POEM in asymptomatic patients. |
| Gastroenterology |
meta-analyses and systematic reviews
| Gastrointest Endosc |
|---|
Efficacy of fully covered self-expandable metal stents and comparison with conventional management for ERCP-related type II perforations: A systematic review and meta-analysis. This meta-analysis demonstrates superiority of FCSEMS in achieving better outcomes compared to conventional management of Type II perforations. |
RCT, clinical trials, retrospective studies, etc…
| Aliment Pharmacol Ther |
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Effect of Nucleos(t)ide Analogues Withdrawal on Survival Outcomes in Patients With Hepatitis B Virus-Related Acute-on-Chronic Liver Failure. NA withdrawal is an independent risk factor for death in patients with HBV-ACLF, underlining the importance of adherence to NA therapy in patients with chronic hepatitis B. |
Mepolizumab Improves Histologic Severity as Measured by the EoEHSS in Adolescents and Adults With Eosinophilic Oesophagitis in a Multicenter, Randomised, Double-Blind, Placebo-Controlled Clinical Trial. HSS correlated with endoscopic severity for grade (R = 0.45, p < 0.001) and stage (R = 0.47, p < 0.001), but improvement was primarily limited to the eosinophil-dependent HSS features. Eosinophil-focused treatments alone may not provide comprehensive treatment response across multiple outcome domains in EoE. |
Underdiagnosis of Alpha-1 Antitrypsin Deficiency in Cirrhotic Liver Transplant Candidates: Findings From a Multicenter Retrospective Study. AATD remains underdiagnosed in pre-LT assessments and is poorly understood amongst practitioners in France. Improved screening can enhance patient management, especially with emerging potentially curative treatments. |
| Endoscopy |
Surgery versus endoscopy with digital single-operator cholangioscopy-guided therapy for Mirizzi syndrome: The SEIZE study. Our study demonstrates that the use of dSOC for Mirizzi syndrome is effective, showing superior safety despite being used to treat patients with more underlying comorbidity. dSOC seems valuable in downgrading the extent of subsequent surgery, by potentially reducing the need for hepaticojejunostomy and conversion to open surgery. |
| Gastroenterology |
Efficacy of ACupuncTure in Irritable bOwel syNdrome (ACTION): a multi-centre randomized controlled trial. Acupuncture improved abdominal pain and stool consistency in patients with IBS-D, with sustained efficacy over 18 weeks. The results of this trial suggest that acupuncture may serve as an alternative treatment for IBS-D. (ACTION Chinese Clinical Trial Registry number, ChiCTR2100044762). |
| Gut |
Commensal <i>Bacteroides</i> T6SS alleviate GI-aGVHD via mediating gut microbiota composition and bile acids metabolism. T6SS in commensal bacteria could modulate bile acid metabolism, potentially impacting aGVHD outcomes and offering a novel target for therapeutic interventions. |
| Hepatology |
Bariatric surgery for metabolic dysfunction-associated steatotic liver disease (MASLD): Current knowledge of mechanisms. Given the mounting evidence from preclinical research, clinical trials and advanced biotechnologies emerging in recent years, refined histological and cellular in-depth characterization in MBS-treated MASLD is anticipated. This review summarizes the current knowledge on the pathogenic and therapeutic effects of MBS on MASLD, with the hope of inspiring further mechanistic and translational studies. |
| J Hepatol |
Personalized survival benefit estimation from living donor liver transplantation with a novel machine learning method for confounding adjustment. DPSM provides an effective approach for creating RCT-like comparability from observational data to predict which patients will benefit most from LDLT. This novel ML-based methodology enables personalized survival predictions while minimizing confounders and offers clinicians a new tool to more confidently evaluate treatment effects. |
Plenty of the editorials are available as full text through the publisher website using the provided link
| Aliment Pharmacol Ther |
|---|
| Gastrointest Endosc |
| Gut |
Gastrointestinal microbiota and inflammasomes interplay in health and disease: a gut feeling. Besides the standard experimental approaches, this complex network of interactions is now being addressed by Artificial intelligence, which emphasises the profound impact of the gut microbiota on GI health, cancer progression and brain function, opening new avenues for therapeutic intervention in GI diseases, cancer and neurological disorders. Ultimately, microbiota-inflammasome interactions manage a regulatory framework that influences inflammation, cancer progression and systemic diseases, positioning it as both a mediator and a promising therapeutic target in GI malignancies and systemic diseases of the central nervous system. |
misc publications eg case reports, tools of the trade, images of the month, etc…
| Am J Gastroenterol |
|---|
| Clin Gastroenterol Hepatol |
| Endoscopy |
| Gastroenterology |
| Gastrointest Endosc |
| Gut |
| Hepatology |
| J Hepatol |
Letters to the editors and authors’ replies
| Aliment Pharmacol Ther |
|---|
| Clin Gastroenterol Hepatol |
| J Hepatol |