Fri Jun 06 2025

49 articles - From Friday May 30 2025 to Friday Jun 06 2025

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Guidelines

Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…

Endoscopy

Curriculum for training in peroral endoscopic myotomy (POEM) in Europe (Part II) - Best Practice Techniques: European Society of Gastrointestinal Endoscopy (ESGE) Position Statement.

14: In the absence of adverse events, resume fluids on day 1, soft diet on day 3, and normal diet on day 7 post-POEM. 15: ESGE recommends against the routine use of standard or computed tomography fluoroscopic esophagrams after POEM in asymptomatic patients.

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Gastroenterology

An International Consensus on Appropriate Management of Corticosteroids in Clinical Trials in Inflammatory Bowel Disease.

These recommendations will serve to optimize trial design and facilitate appropriate, acceptable, and standardized RCT corticosteroid handling practices.

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Meta-analysis

meta-analyses and systematic reviews

Gastrointest Endosc

Efficacy of fully covered self-expandable metal stents and comparison with conventional management for ERCP-related type II perforations: A systematic review and meta-analysis.

This meta-analysis demonstrates superiority of FCSEMS in achieving better outcomes compared to conventional management of Type II perforations.

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Original articles

RCT, clinical trials, retrospective studies, etc…

Aliment Pharmacol Ther

Effect of Nucleos(t)ide Analogues Withdrawal on Survival Outcomes in Patients With Hepatitis B Virus-Related Acute-on-Chronic Liver Failure.

NA withdrawal is an independent risk factor for death in patients with HBV-ACLF, underlining the importance of adherence to NA therapy in patients with chronic hepatitis B.

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Mepolizumab Improves Histologic Severity as Measured by the EoEHSS in Adolescents and Adults With Eosinophilic Oesophagitis in a Multicenter, Randomised, Double-Blind, Placebo-Controlled Clinical Trial.

HSS correlated with endoscopic severity for grade (R = 0.45, p < 0.001) and stage (R = 0.47, p < 0.001), but improvement was primarily limited to the eosinophil-dependent HSS features. Eosinophil-focused treatments alone may not provide comprehensive treatment response across multiple outcome domains in EoE.

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Underdiagnosis of Alpha-1 Antitrypsin Deficiency in Cirrhotic Liver Transplant Candidates: Findings From a Multicenter Retrospective Study.

AATD remains underdiagnosed in pre-LT assessments and is poorly understood amongst practitioners in France. Improved screening can enhance patient management, especially with emerging potentially curative treatments.

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Endoscopy

Surgery versus endoscopy with digital single-operator cholangioscopy-guided therapy for Mirizzi syndrome: The SEIZE study.

Our study demonstrates that the use of dSOC for Mirizzi syndrome is effective, showing superior safety despite being used to treat patients with more underlying comorbidity. dSOC seems valuable in downgrading the extent of subsequent surgery, by potentially reducing the need for hepaticojejunostomy and conversion to open surgery.

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Gastroenterology

AAV-mediated silencing of Sox4 leads to long-term amelioration of liver phenotypes in mouse models of Alagille syndrome.

Preclinical studies provide proof of principle for postnatal AAV-mediated Sox4 knockdown in TBG + cells as a therapeutic approach for ALGS liver disease.

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Efficacy of ACupuncTure in Irritable bOwel syNdrome (ACTION): a multi-centre randomized controlled trial.

Acupuncture improved abdominal pain and stool consistency in patients with IBS-D, with sustained efficacy over 18 weeks. The results of this trial suggest that acupuncture may serve as an alternative treatment for IBS-D. (ACTION Chinese Clinical Trial Registry number, ChiCTR2100044762).

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Gut

Commensal <i>Bacteroides</i> T6SS alleviate GI-aGVHD via mediating gut microbiota composition and bile acids metabolism.

T6SS in commensal bacteria could modulate bile acid metabolism, potentially impacting aGVHD outcomes and offering a novel target for therapeutic interventions.

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Hepatology

Bariatric surgery for metabolic dysfunction-associated steatotic liver disease (MASLD): Current knowledge of mechanisms.

Given the mounting evidence from preclinical research, clinical trials and advanced biotechnologies emerging in recent years, refined histological and cellular in-depth characterization in MBS-treated MASLD is anticipated. This review summarizes the current knowledge on the pathogenic and therapeutic effects of MBS on MASLD, with the hope of inspiring further mechanistic and translational studies.

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J Hepatol

Personalized survival benefit estimation from living donor liver transplantation with a novel machine learning method for confounding adjustment.

DPSM provides an effective approach for creating RCT-like comparability from observational data to predict which patients will benefit most from LDLT. This novel ML-based methodology enables personalized survival predictions while minimizing confounders and offers clinicians a new tool to more confidently evaluate treatment effects.

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link

Aliment Pharmacol Ther

Editorial: Chronic Hepatitis B at the Intersection of Immigration, Acculturation and Social Determinants of Health.

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Gastrointest Endosc

Endoscopic Approaches to Reduce the Incidence of Interval Colon Cancer.

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Gut

Gastrointestinal microbiota and inflammasomes interplay in health and disease: a gut feeling.

Besides the standard experimental approaches, this complex network of interactions is now being addressed by Artificial intelligence, which emphasises the profound impact of the gut microbiota on GI health, cancer progression and brain function, opening new avenues for therapeutic intervention in GI diseases, cancer and neurological disorders. Ultimately, microbiota-inflammasome interactions manage a regulatory framework that influences inflammation, cancer progression and systemic diseases, positioning it as both a mediator and a promising therapeutic target in GI malignancies and systemic diseases of the central nervous system.

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Miscellaneous

misc publications eg case reports, tools of the trade, images of the month, etc…

Am J Gastroenterol

PEG Tube Gone Rogue: An Unusual Cause of Acute Pancreatitis.

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Pill Esophagitis Resulting in Esophageal Mucosal Dissection and Stricture.

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Primary Biliary Cholangitis in 2025: A New Frontier.

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Clin Gastroenterol Hepatol

Adverse Events After Surveillance Colonoscopy in Older Adults In A Large Integrated Health System in the United States.

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Endoscopy

A novel treatment for radiation proctopathy using monopolar spray coagulation with a polypectomy snare tip.

Pubmed   Journal   ReadQx   PMC

An early-detected intraductal papillary squamous neoplasm of the pancreas under peroral pancreatoscopy.

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Be cautious with the semilunar fold! Endoscopic perforation after cap-suction pseudopolyp formation for underwater en bloc resection of a big cecal lesion.

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Beyond the hype: understanding the limits of perceived benefits in endoscopic ultrasound-guided portal pressure gradient measurement.

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Drainage for complete obstruction of the posterior bile duct after pancreatoduodenectomy with a forward-viewing echoendoscope.

Pubmed   Journal   ReadQx   PMC

Endoscopic resection of a large distal common bile duct adenoma with focal malignancy: palliative approach in a high-risk patient.

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Endoscopic septotomy for a rare colorectal anastomotic complication after elective laparoscopic sigmoidectomy for diverticular disease.

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Endoscopic ultrasonography of a multiseptate gallbladder: differentiation from adenomyomatosis of the gallbladder.

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Endoscopic ultrasound-guided embolization with imatinib for duodenal gastrointestinal stromal tumors in inoperable or treatment-unwilling patients.

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Endoscopic ultrasound-guided embolization: Successful management of hemorrhage from gastric artery aneurysm rupture.

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Endoscopy E-Videos - recently published.

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Innovative sphincterotomy knife and indigo carmine strategy for bile duct stones in a patient with surgically altered anatomy.

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Linear endoscopic ultrasonography-guided biopsy forceps removal of a fishbone from the muscularis propria.

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Management of delayed perforation after esophageal endoscopic submucosal dissection using a vacuum-assisted closure stent.

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Reflections on endoscopic ultrasound-guided drainage for infected walled-off necrosis.

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Underwater endoscopic submucosal dissection for recurrent superficial esophageal cancer at the site of stenosis after endoscopic resection.

Pubmed   Journal   ReadQx   PMC

Gastroenterology

A Practical Guide to Incorporating a Psychologist into a Gastroenterology Practice.

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A Pragmatic Trial Comparing Uptake and Cancer Mortality between Invitation to Colonoscopy and Invitation to Fecal Immunochemical Testing Approaches.

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Relationship of Intra-Pancreatic Fat Deposition With Pancreatic Cancer Differs According to Carcinoma Types.

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Gastrointest Endosc

Endoscopic U-Shaped Stent Placement in a Six-Year-Old Girl with Chronic Pancreatitis and Incomplete Pancreas Divisum.

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Gut

A black liver.

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Hepatology

Letter to the editor: Considerations on the use of the liver transplant comorbidity index (LTCI).

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Letter to the editor: Critical considerations in estimating HCC risk in PSC.

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Reply: Liver stiffness progression comparison between diabetics and non-diabetics with biopsy-proven metabolic dysfunction-associated steatosis.

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J Hepatol

Harnessing spatial immunity to predict recurrence in hepatocellular carcinoma.

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Rethinking hepatic encephalopathy: Gut microbes, neurotoxins and the therapeutic horizon.

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Letters&Replies

Letters to the editors and authors’ replies

Aliment Pharmacol Ther

Editorial: Chronic Hepatitis B at the Intersection of Immigration, Acculturation, and Social Determinants of Health-Authors' Reply.

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Clin Gastroenterol Hepatol

Balancing Novelty and Pragmatism: Integrating GEMA-AI into Clinical Workflows.

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J Hepatol

Challenges in Applying MASLD Risk Algorithms in Pregnancy: A Call for Adaptation and Inclusion.

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Re: Differential HBV RNA and HBcrAg patterns in untreated patients with chronic hepatitis delta.

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